Tag Archives: PET

Pets and cognitive decline

“I talk to our dog; I talk to our cats. Mind you that these are not deep conversations, such as the ones I have with my wife. It turns out, however, that the presence of pets in the house can have profound effects on slowing the verbal cognitive decline in older individuals. There is one catch: you have to be living alone.”

“I believe this study underscores something that is all too real about disconnectedness in our modern culture. Loneliness and isolation are significant threats to physical and mental health. Recently, the US Surgeon General issued an advisory on the public health crisis of loneliness, isolation, and lack of connection in our country.1 Primary care clinicians need to be aware of this and ask patients specifically about their social networks and feelings of loneliness.”

Ollie and Maxine

“Reaching out to, and building connections with family, friends, and — importantly — others in our communities who are disconnected, is vitally important to health and well-being. And, in some cases, a household pet can be a big benefit. I tell this to my dog and cats all the time.”

https://www.practiceupdate.com/content/pet-ownership-living-alone-and-cognitive-decline-among-adults-aged-50-years-and-older/160896

Disease Modifying Therapy for Alzheimer’s

“The long-awaited era of disease-modifying therapy for Alzheimer’s disease has finally arrived and will substantially impact how the disease is perceived and managed, although these new treatments will pose challenges for equitable access. The drugs closest to widespread clinical implementation are lecanemab and donanemab—intravenous monoclonal antibodies that remove β-amyloid plaques from the brain and can slow cognitive and functional decline.”

Donanemab appears to be the ‘easier’ choice. MMSE 20-28, Monthly Infusion (vs q2Wk), Stop when Amyloid PET is negative. Probably need to get APOE on these patients.
https://doi.org/10.1016/S1474-4422(23)00274-0

Contact Dr. Varipapa’s office if you are interested in exploring this option.