Tag Archives: parkingsons

What Ozempic Really Does to Your Brain

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Mounjaro just approved for Sleep Apnea

“IF YOU TAKE a GLP-1 agonist like Ozempic or Zepbound, you can see changes to your waistline and your blood sugar within weeks. What might be less obvious is how the drug is affecting your brain. Research suggests these popular weight-loss medications can influence everything from daily behavior to risk of age-related memory loss, and neuroscientists are working overtime to discover exactly how these drugs affect the brain.


“It is a hot topic,” says Kevin Williams, Ph.D., a neuroscientist at the University of Texas Medical Branch. “If you can understand how these drugs are accessing the brain and where they are acting, then potentially that could guide future drug development to be able to better target these regions.”

https://www.menshealth.com/health/a63249412/what-ozempic-does-to-your-brain/

Why do obesity drugs seem to treat so many other ailments?

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“Curbing addiction isn’t the only potential extra benefit of GLP-1 drugs.

Mounjaro Zepbound Ozempic Wegovy

Other studies have suggested they can reduce the risk of death, strokes and heart attacks for people with cardiovascular disease or chronic kidney ailments, ease sleep apnea symptoms and even slow the development of Parkinson’s disease. There are now hundreds of clinical trials testing the drugs for these conditions and others as varied as fatty liver disease, Alzheimer’s disease, cognitive dysfunction and HIV complications.”

https://www.nature.com/articles/d41586-024-03074-1

New wearable treatment for Parkinson’s

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The science behind the CUE1

Focused stimulation for Parkinson’s
This phenomenon was first described in the 19th century when Professor Jean-Martin Charcot noticed an improvement in his Parkinson’s patients after a bumpy carriage ride.”

https://charconeurotech.com/the-science/

Game Changers: Ozempic, Wegovy, Mounjaro, Zepbound

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GLP-1 agents such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) are game-changers. In addition to weight loss, they may reduce neurodegenerative diseases, such as Parkinson’s and Alzheimers dementia, due to a reduction in metabolic syndrome, reduction in vascular events and neuroprotective effects.

“GLP-1 plays important role in augmenting insulin signalling inside the brain. GLP-1 receptors, present inside the brain, are also involved in cognition, synaptic transmission in hippocampal neurons, and cell apoptosis. Overexpression of this receptor is responsible for cognition enhancement and neuroprotection, while deficiency increases the chances of seizure and neurodegeneration (81, 82). Therefore, GLP-1 receptors are considered as validated target for exploring candidates with better neuroprotection and cognition enhancing abilities (83).”

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9159769/