Tag Archives: Memory

Why do obesity drugs seem to treat so many other ailments?

“Curbing addiction isn’t the only potential extra benefit of GLP-1 drugs.

Mounjaro Zepbound Ozempic Wegovy

Other studies have suggested they can reduce the risk of death, strokes and heart attacks for people with cardiovascular disease or chronic kidney ailments, ease sleep apnea symptoms and even slow the development of Parkinson’s disease. There are now hundreds of clinical trials testing the drugs for these conditions and others as varied as fatty liver disease, Alzheimer’s disease, cognitive dysfunction and HIV complications.”

https://www.nature.com/articles/d41586-024-03074-1

Memory Loss Isn’t the Only Sign of Dementia

Here are five other common red flags to look out for.

Running red lights. Falling for scams. Shutting out friends.

Memory loss is the most well-known symptom of dementia, particularly Alzheimer’s disease. But experts say there are other warning signs that can signal early brain changes — ones that are especially important for types of dementia where forgetfulness is not the primary symptom.

1. Financial Problems

People with dementia can experience money problems or declining credit scores years before memory loss, or other cognitive symptoms, emerge.

2. Sleep Issues

Sleep disorders can become more common as people age, and older adults tend to sleep more lightly and go to bed and wake up a little earlier than they used to — that is completely normal. But if there are dramatic changes in someone’s sleep habits, where they are starting their morning at 3 a.m. or are unable to stay awake during the day, it can be a sign of dementia.

3. Personality Changes

In a study published last year, researchers found that people with dementia experienced slight drops in extroversion, agreeableness and conscientiousness before they showed any signs of cognitive impairment.

4. Driving Difficulties

Along with handling finances, driving is one of the most complex cognitive behaviors people perform every day. Ganesh Babulal, an associate professor of neurology at Washington University in St. Louis, has demonstrated in his research that problems behind the wheel can manifest years before they do elsewhere.

5. Loss of Smell

Parts of the brain that control smell, known as the olfactory system, are among some of the first areas damaged in Alzheimer’s disease and dementia with Lewy bodies; this is also the case for Parkinson’s disease. Many people with these conditions begin to lose their sense of smell years, or even decades, before other symptoms appear.

Covid Brain

This week in key Covid publications:

—Young, healthy individuals with mild cases had objective cognitive deficits at 1-year that they did not perceive

—Older, hospitalized adults with severe Covid had an equivalent of 20 years of decline in cognitive performance at 1-year follow-up

—A nasal vaccine (2 doses) blocked infections for at least 3 months and was effective across 10 different variants

—Reinfections increase the risk of LongCovid

—mRNA shots don’t induce long-lived plasma cells, but we don’t know if this is true with other vaccine platforms

The potential of a Covid hit to the brain, affecting cognitive function, has been clearly reinforced by the 2 new studies, with the whole spectrum of mild cases among healthy, young, people to older, severe Covid hospitalized patients.

https://erictopol.substack.com/p/covid-brain

Home Care Resources

Are there programs in Delaware that will allow me to hire my own attendant?
https://dhss.delaware.gov/dsaapd/faq_attendant.html

Can I get paid for being a caregiver for a family member or friend?
https://dhss.delaware.gov/dsaapd/faq_attendant2.html

Delaware Division of Aging Contact Information
Phone: 1-800-223-9074
Email: DelawareADRC@delaware.gov

https://dhss.delaware.gov/dsaapd/contact.html

Long Term Care Medicaid Programs
https://dhss.delaware.gov/dmma/ltcmedicaid.html

Medicaid and veterans programs can help alleviate the financial burden of family caregiving
https://www.aarp.org/caregiving/financial-legal/info-2017/you-can-get-paid-as-a-family-caregiver.html

★ Delaware Medicaid & Medical Assistance

Understanding Long-Term Care Insurance
https://www.aarp.org/caregiving/financial-legal/info-2021/understanding-long-term-care-insurance.html

Long-Term Care Cost Calculator
https://www.aarp.org/caregiving/financial-legal/long-term-care-cost-calculator/?cmp=RDRCT-672c8608-20210611

Seven Simple Ways to Reduce your risk of Dementia

The latest research is revealing clues about how you might be able to lower your chances of getting dementia. Here’s what the science says about keeping your mind sharp

  1. Keep your eyes on the move (and hearing)
  2. Keep on learning
  3. Surround yourself with others
  4. Be conscientious, not neurotic
  5. Reduce your exposure to air pollution
  6. Make sleep your priority
  7. Exercise and eat healthy

Click the link for more details
https://apple.news/ApqEPmWXwQ9ymdNIrQ7TM3g

DMV Reporting Laws Update

Delaware finally amended its DMV reporting laws to no longer require mandatory reporting of patients with seizures, loss of consciousness or other medical conditions.

Physicians should continue to use their medical judgment when dealing with patients with potentially impaired driving capabilities and may continue to send reports to DMV on a case by case basis.

House Bill 314, which updates the outdated mandatory reporting requirements for loss of consciousness due to a central nervous system condition, was supported by MSD and had passed both chambers. On Friday, August 2nd, Governor Carney signed the legislation into law.

MSD President, Robert Varipapa, MD, testified that the mandatory reporting system did not function effectively, especially in the emergency room setting where individuals are often inappropriately reported to the Division of Motor Vehicles (DMV) resulting in overworked DMV personnel and a substantial backlog in the physician’s office. 

It was also noted that the mandatory reporting requirement placed physicians in the awkward role of being a law enforcement officer, leading some patients being hesitant to truthfully disclose seizures or other episodes of loss of consciousness to their physician due to fear of losing their license. 

MSD testimony stated that physicians and other medical professionals should still report cases to the DMV based on medical evidence, not only limited to repeated loss of consciousness, but also other conditions such as dementia and stroke. 

This Act does all of the following: 

(1) Allows for all licensed practitioners (physician, nurse practitioner, or physician assistant) who are treating a driver for a medical condition to report findings and sign Division paperwork, which mirrors verbiage found in Title 24; 

(2) Updates the name of Medical Council to Board of Medical Licensure and Discipline which ensures compliance with code in handling of individual cases; and 

(3) Changes the Secretary of Health and Social Services to Secretary of Transportation for determining the status of driver’s license for individuals with a potential medical condition which allows for quicker response and ensures the confidentiality of a driver. Lastly it removes a section from the Medical Licensure Act consistent with the other provisions of the bill.

A vaccine that could lower dementia risk has been hiding in plain sight

Why the vaccine may protect against dementia

Offit and other experts said there are two possible reasons that the shingles vaccine might protect against dementia. First, previous research suggests that herpes infection might play a role in the development of dementia.

Shingrix dramatically decreases the reactivation of the herpes virus that causes chickenpox. It’s 97 percent effective at preventing shingles in people ages 50 to 69 with healthy immune systems, according to the CDC.

Experts also hypothesize there might be something about the particular way Shingrix stimulates the body’s immune system against shingles that decreases the chances of dementia.”

https://www.washingtonpost.com/wellness/2024/07/30/shingles-vaccine-lower-dementia-risk/

Another very expensive drug for Alzheimer’s disease with lots of side effects and unclear benefit

FDA OKs Another Drug for Early Alzheimer’s Disease

The FDA approved donanemab (Kisunla) for the treatment of adults with early symptomatic Alzheimer’s disease with confirmed amyloid pathology, the agency announcedopens in a new tab or window Tuesday. This includes Alzheimer’s patients with mild cognitive impairment and mild dementia.

The once-monthly treatment is the only anti-amyloid agent with evidence to support stopping therapy when amyloid plaques

https://www.medpagetoday.com/neurology/alzheimersdisease/110934

Alzheimer’s blood test catches 90% of early dementia

In the new study, the p-tau217 test was combined with another blood biomarker for Alzheimer’s called the amyloid 42/40 ratio, which measures two types of amyloid proteins, another biomarker of Alzheimer’s disease.

https://www.cnn.com/2024/07/28/health/alzheimer-blood-test-p-tau-217-wellness/index.html

Dementia is not a death

For some, it marks a new beginning

Advocates are reframing the syndrome as a different way of being – one in which potential for growth and connection endures

They argue that dementia is not a hopeless affliction, and that post-diagnostic support should become more humane and scientific. Some are even calling for the condition to be completely reimagined.

One patient, quoted in the dementia expert John Zeisel’s book ‘I’m Still Here’ goes so far as to describe it as ‘a new stage in a wonderful life, no less challenging or interesting than all the earlier stages’.

https://psyche.co/ideas/dementia-is-not-a-death-for-some-it-marks-a-new-beginning