Tag Archives: brain

Memory Loss Isn’t the Only Sign of Dementia

Here are five other common red flags to look out for.

Running red lights. Falling for scams. Shutting out friends.

Memory loss is the most well-known symptom of dementia, particularly Alzheimer’s disease. But experts say there are other warning signs that can signal early brain changes — ones that are especially important for types of dementia where forgetfulness is not the primary symptom.

1. Financial Problems

People with dementia can experience money problems or declining credit scores years before memory loss, or other cognitive symptoms, emerge.

2. Sleep Issues

Sleep disorders can become more common as people age, and older adults tend to sleep more lightly and go to bed and wake up a little earlier than they used to — that is completely normal. But if there are dramatic changes in someone’s sleep habits, where they are starting their morning at 3 a.m. or are unable to stay awake during the day, it can be a sign of dementia.

3. Personality Changes

In a study published last year, researchers found that people with dementia experienced slight drops in extroversion, agreeableness and conscientiousness before they showed any signs of cognitive impairment.

4. Driving Difficulties

Along with handling finances, driving is one of the most complex cognitive behaviors people perform every day. Ganesh Babulal, an associate professor of neurology at Washington University in St. Louis, has demonstrated in his research that problems behind the wheel can manifest years before they do elsewhere.

5. Loss of Smell

Parts of the brain that control smell, known as the olfactory system, are among some of the first areas damaged in Alzheimer’s disease and dementia with Lewy bodies; this is also the case for Parkinson’s disease. Many people with these conditions begin to lose their sense of smell years, or even decades, before other symptoms appear.

Neuroanatomy 101

“The Lichtman laboratory at Harvard University and the Connectomics at Google team are releasing the “H01” dataset and companion paper. H01 is a 1.4 petabyte volume of a small sample of human brain tissue.

The sample was imaged at nanoscale-resolution by serial section electron microscopy, reconstructed and annotated by automated computational techniques, and analyzed for preliminary insights into the structure of human cortex.”

http://h01-release.storage.googleapis.com/landing.html/landing.html

Found: the dial in the brain that controls the immune system

Scientists identify the brain cells that regulate inflammation, and pinpoint how they keep tabs on the immune response.

Scientists have long known that the brain plays a part in the immune system — but how it does so has been a mystery. Now, scientists have identified cells in the brainstem that sense immune cues from the periphery of the body and act as master regulators of the body’s inflammatory response

The results in Nature suggest that the maintains a delicate balance between the molecular signals that promote inflammation and those that dampen it — a finding that could lead to treatments for autoimmune diseases and other conditions caused by an excessive immune response

The discovery is akin to a black-swan event 🧐

https://www.nature.com/articles/d41586-024-01259-2

New Frontier or Boondoggle?

Neuralink implants brain chip in first human

“The first human patient has received an implant from brain-chip startup Neuralink on Sunday and is recovering well, the company’s billionaire founder Elon Musk said.

“Initial results show promising neuron spike detection,” Musk said in a post on the social media platform X on Monday.

Spikes are activity by neurons, which the National Institute of Health describes as cells that use electrical and chemical signals to send information around the brain and to the body.”

https://www.reuters.com/technology/neuralink-implants-brain-chip-first-human-musk-says-2024-01-29/