GLP-1 agents such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) are game-changers. In addition to weight loss, they may reduce neurodegenerative diseases, such as Parkinson’s and Alzheimers dementia, due to a reduction in metabolic syndrome, reduction in vascular events and neuroprotective effects.
“GLP-1 plays important role in augmenting insulin signalling inside the brain. GLP-1 receptors, present inside the brain, are also involved in cognition, synaptic transmission in hippocampal neurons, and cell apoptosis. Overexpression of this receptor is responsible for cognition enhancement and neuroprotection, while deficiency increases the chances of seizure and neurodegeneration (81, 82). Therefore, GLP-1 receptors are considered as validated target for exploring candidates with better neuroprotection and cognition enhancing abilities (83).”
Want to slow memory loss after 60? A multivitamin may be the answer.
A group taking a multivitamin was two years younger in memory function than a group taking a placebo, research shows
It is the third in a series of studies assessing the cognitive effects of a daily multivitamin on older adults. And a systematic review, or meta-analysis, of the three studies accompanying the most recent paper said their cumulative results were similar: The group taking a multivitamin was two years younger in memory function compared with the group taking a placebo.
And don’t forget exercising and keeping your mind busy by reading and doing puzzles. If you are retired and watching cable TV and Fox News all day, doubt balanced meals or vitamins are going to help.
TL: DR My two favorites: Autosleep on iPhone and Sleep as Android
In today’s fast-paced world, getting a good night’s sleep is more important than ever. To help you monitor and improve your sleep patterns, there are numerous sleep tracker apps available. My recommendations are Autosleep for iPhone and Sleep as Android. In this blog post, we’ll compare these two sleep tracker apps, highlighting their features, user interfaces, and overall performance to help you make an informed choice for tracking your sleep.
Autosleep
Autosleep is a dedicated sleep tracking app exclusively available for iOS devices. Developed by Tantsissa, it offers a user-friendly interface and a robust set of features tailored for iPhone and Apple Watch users.
Automatic Tracking: Autosleep uses advanced algorithms to automatically detect when you fall asleep and wake up, eliminating the need for manual input. Sleep Score: The app calculates a Sleep Score based on the quality and duration of your sleep, providing insights into your sleep patterns. Sleep Rings: It visualizes your sleep data in a ring format, making it easy to understand at a glance. Detailed Sleep Analysis: Autosleep provides in-depth statistics about your sleep cycles, heart rate, and more. Integration with Health App: The app seamlessly integrates with the Apple Health app, allowing you to centralize your health data. User Interface: Autosleep boasts an intuitive and visually appealing interface, making it easy for users to navigate through their sleep data. The Sleep Rings feature is particularly engaging and informative. https://autosleepapp.tantsissa.com/home
Sleep as Android
Sleep as Android is a versatile sleep tracking app available for Android devices. Developed by Urbandroid, it offers a wide range of features and is known for its extensive customization options.:
Comprehensive Tracking: Sleep as Android tracks your sleep cycles, snoring, and even your sleep talk to provide a holistic view of your sleep quality. Smart Alarms: The app offers smart alarms that wake you up at the optimal time within a set time window, reducing grogginess. Integration with Wearables: It supports various wearables and sensors, allowing you to use devices like smartwatches and fitness trackers for sleep tracking. Sleep Notes: You can add custom notes about your sleep, which can help identify patterns and triggers affecting your sleep. Captivating Sleep Charts: Sleep as Android generates detailed sleep charts and graphs for in-depth analysis. User Interface: While Sleep as Android offers a wealth of features, some users may find its interface less intuitive compared to Autosleep. However, its customization options make it suitable for those who prefer to tailor their sleep tracking experience. https://sleep.urbandroid.org
Summary
Both Apps are excellent sleep trackers. Autosleep happily does not require a subscription and only costs $5.99, a worthwhile investment. Autosleep works much better if you have an Apple Watch. Sleep for Android requires a subscription or initial $40 one time payment and also works much better if you have a wearable device.
Please contact your DME supplier if you have a ResMed Mask.
The U.S. Food and Drug Administration (FDA) on Thursday classified the recall of certain respiratory masks made by ResMed (RMD.N) as most serious as their use could cause major injuries or death.
A preliminary review of side effects from popular drugs used to treat diabetes and obesity shows no link with suicidal thoughts or actions, the U.S. Food and Drug Administration said Thursday.
But the agency also said officials cannot definitively rule out that “a small risk may exist” and that they’ll continue to look into reports regarding more than a dozen drugs, including Ozempic, Wegovy and Mounjaro. Patients taking the drugs should report any concerns to health care providers, the FDA said. https://apnews.com/article/wegovy-ozempic-obesity-suicide-thoughts-fda-fbe7b158e78c199f8f8d3a551dcaa60d
“Persistent cognitive deficits even in those without clinical neurological complications. When compared to normative age-matched data, these deficits were equivalent in magnitude to ageing from 50 to 70 years of age (1). This study indicated cognitive deficits were associated with the severity of the initial infective insult, post-acute mental health status, and a history of #COVID-19 associated #Encephalopathy, with strong concordance between subjective and objective deficits.”
Opinion: The U.S. is facing the biggest COVID wave since Omicron. Why are we still playing make-believe?
“The pandemic is far from over, as evidenced by the rapid rise to global dominance of the JN.1 variant of SARS-CoV-2. This variant is a derivative of BA.2.86, the only other strain that has carried more than 30 new mutations in the spike protein since Omicron first came on the scene more than two years ago. This should have warranted designation by the World Health Organization as a variant of concern with a Greek letter, such as Pi.”
All of New York is hacking. We sent Rachel Sklar on a mission to find out what can help—if anything.
I was at a long-awaited panel discussion at my friends’ private home, listening to Senator Kristen Gillibrand speak about paid leave and reproductive rights with women’s health entrepreneurs Priyanka Jain and Alessandra Henderson, when I first heard it: The Cough.
Henderson, the founder of a women’s health company called Elektra Health, coughed discreetly from the makeshift stage. Then she coughed again. It was dry and quick and frequent. Every so often, she would turn her head, raise her hands, and behind the swishy curtain of her chic blonde bob, cough. A woman stole over and slipped her a cough drop. Gillibrand had warmed up and was on a tear about TikTok. (Not a fan, by the way.) And still, discreetly but certainly not imperceptibly, coughing. Henderson did not otherwise seem sick. She was a power woman on a panel with a Senator, in peak form, but what can I say: these days, you notice the cough.
“A growing consensus is emerging that receiving multiple doses of the COVID vaccine before an initial infection can dramatically reduce the risk of long-term symptoms. Although the studies disagree on the exact amount of protection, they show a clear trend: the more shots in your arm before your first bout with COVID, the less likely you are to get long COVID.”
“When I asked friends if they’re noticing coughs more or suffering themselves, they regaled and horrified me with their coughing fits. One had COVID-triggered asthma and an eight-month cough (under control now, thanks to two inhalers and a trip to the pulmonologist). Another was a lifelong mucous-heavy cougher whose tips included “Chest Physical Therapy” which uses gravity and chest/back percussion to get phlegm to loosen and drain (she lies prone hanging over her bed while “banging her back”).”
CNMRI: Neurology, Sleep Medicine, MRI 