This week in key Covid publications:

—Young, healthy individuals with mild cases had objective cognitive deficits at 1-year that they did not perceive

—Older, hospitalized adults with severe Covid had an equivalent of 20 years of decline in cognitive performance at 1-year follow-up

—A nasal vaccine (2 doses) blocked infections for at least 3 months and was effective across 10 different variants

—Reinfections increase the risk of LongCovid

—mRNA shots don’t induce long-lived plasma cells, but we don’t know if this is true with other vaccine platforms

The potential of a Covid hit to the brain, affecting cognitive function, has been clearly reinforced by the 2 new studies, with the whole spectrum of mild cases among healthy, young, people to older, severe Covid hospitalized patients.

https://erictopol.substack.com/p/covid-brain