(The GLP1 drugs are favorites for Dr Varipapa, improving health in so many ways!)

A large trial showed that semaglutide, sold as Ozempic for diabetes and as Wegovy for obesity, was better than any current medications in alleviating symptoms.

(Dr Varipapa suspects Mounjaro and Zepbound to have similar if not better benefit as it is even better for treatment of obesity!)

The blockbuster drug semaglutide, sold as Ozempic for diabetes and as Wegovy for weight loss, now has a new proven benefit: It markedly soothed knee pain in people who are obese and have moderate to severe osteoarthritis, according to a large study.

The effect was so pronounced that some arthritis experts not involved with the clinical trial were taken aback.

“The magnitude of the improvement is of a scope we haven’t seen before with a drug,” said Dr. Bob Carter, deputy director of the National Institute of Arthritis and Musculoskeletal and Skin Diseases. “They had an almost 50 percent reduction in their knee pain. That’s huge.”